Pernilla Wittung-Stafshede Selected Research

Amyloidogenic Proteins

1/2021	Macromolecular crowding modulates α-synuclein amyloid fiber growth.
1/2020	Crosstalk Between Alpha-Synuclein and Other Human and Non-Human Amyloidogenic Proteins: Consequences for Amyloid Formation in Parkinson's Disease.
11/2019	Interaction between Copper Chaperone Atox1 and Parkinson's Disease Protein α-Synuclein Includes Metal-Binding Sites and Occurs in Living Cells.
1/2018	In Vitro Analysis of α-Synuclein Amyloid Formation and Cross-Reactivity.
1/2018	Copper chaperone blocks amyloid formation via ternary complex.
1/2018	Abundant fish protein inhibits α-synuclein amyloid formation.
11/2016	Cross-talk between amyloidogenic proteins in type-2 diabetes and Parkinson's disease.
7/2015	Insulin-degrading enzyme prevents α-synuclein fibril formation in a nonproteolytical manner.
1/2015	Bacterial Chaperones CsgE and CsgC Differentially Modulate Human α-Synuclein Amyloid Formation via Transient Contacts.

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Pernilla Wittung-Stafshede Research Topics

Disease

28	Parkinson Disease (Parkinson's Disease) 06/2022 - 02/2012
16	Neoplasms (Cancer) 12/2021 - 07/2005
8	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 05/2015
7	Breast Neoplasms (Breast Cancer) 12/2021 - 01/2017
5	Neoplasm Metastasis (Metastasis) 12/2021 - 04/2017
5	Hepatolenticular Degeneration (Wilson's Disease) 12/2019 - 11/2008
3	Amyloid Plaque 06/2022 - 05/2015
2	Menkes Kinky Hair Syndrome (Menkes Disease) 04/2021 - 08/2008
2	Alzheimer Disease (Alzheimer's Disease) 01/2020 - 07/2015
2	Acquired Immunodeficiency Syndrome (AIDS) 01/2020 - 02/2009
2	Dehydration (Water Stress) 11/2018 - 06/2008
2	Type 2 Diabetes Mellitus (MODY) 10/2017 - 07/2015
1	Inborn Errors Metabolism (Inborn Errors of Metabolism) 04/2021
1	Disease Progression 05/2020
1	Inborn Genetic Diseases (Disease, Hereditary) 12/2017
1	Rectal Neoplasms (Rectal Cancer) 10/2017
1	Synucleinopathies 12/2016
1	Neuroinflammatory Diseases 12/2016
1	Infections 03/2016
1	Melanoma (Melanoma, Malignant) 01/2014
1	Drug-Related Side Effects and Adverse Reactions 04/2012
1	Genomic Instability 07/2005

Drug/Important Bio-Agent (IBA)

24	SynucleinsIBA 01/2022 - 02/2012
22	Proteins (Proteins, Gene)FDA Link 01/2022 - 06/2008
18	Amyloid (Amyloid Fibrils)IBA 06/2022 - 02/2012
17	CopperIBA 06/2022 - 08/2008
9	Amyloidogenic ProteinsIBA 01/2021 - 01/2015
5	MetalsIBA 01/2020 - 08/2008
4	IonsIBA 06/2022 - 04/2017
4	Biomarkers (Surrogate Marker)IBA 12/2021 - 10/2017
4	Pharmaceutical PreparationsIBA 01/2017 - 04/2011
3	Carrier Proteins (Binding Protein)IBA 05/2020 - 04/2017
3	Copper Transport ProteinsIBA 12/2019 - 11/2008
3	Cisplatin (Platino)FDA LinkGeneric 01/2014 - 04/2011
2	EnzymesIBA 04/2021 - 01/2018
2	alpha-SynucleinIBA 01/2020 - 01/2017
2	Copper-Transporting ATPasesIBA 01/2018 - 11/2008
2	Islet Amyloid PolypeptideIBA 10/2017 - 11/2016
2	Peptides (Polypeptides)IBA 11/2016 - 07/2015
2	DNA (Deoxyribonucleic Acid)IBA 04/2012 - 04/2011
1	tetrathiomolybdate (ammonium tetrathiomolybdate)IBA 12/2021
1	MetallochaperonesIBA 12/2021
1	Mitogen-Activated Protein KinasesIBA 12/2021
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 12/2021
1	Heavy MetalsIBA 10/2021
1	ArsenicIBA 10/2021
1	CadmiumIBA 10/2021
1	SteroidsIBA 04/2021
1	SulfatasesIBA 04/2021
1	Messenger RNA (mRNA)IBA 05/2020
1	LipidsIBA 01/2020
1	AntioxidantsIBA 01/2020
1	ElectrolytesIBA 11/2018
1	Cholera ToxinIBA 11/2018
1	ParvalbuminsIBA 01/2018
1	Adenosine Triphosphatases (ATPase)IBA 12/2017
1	CollagenIBA 10/2017
1	Cysteine (L-Cysteine)FDA Link 04/2017
1	Protein-Lysine 6-Oxidase (Lysyl Oxidase)IBA 04/2017
1	Transcription Factors (Transcription Factor)IBA 01/2017
1	Virulence Factors (Pathogenicity Factors)IBA 03/2016
1	Peptide Hydrolases (Proteases)FDA Link 07/2015
1	AntibodiesIBA 01/2014
1	2-hydroxypyridineIBA 04/2013
1	Antineoplastic Agents (Antineoplastics)IBA 01/2013
1	ChromatinIBA 09/2012
1	LigandsIBA 04/2012
1	PlatinumIBA 04/2012
1	SolventsIBA 02/2009
1	CationsIBA 06/2008
1	Tumor Suppressor Protein p53IBA 07/2005
1	AzurinIBA 07/2005
1	Bacterial Proteins (Bacterial Protein)IBA 07/2005

Therapy/Procedure

1	Therapeutics 01/2020
1	Radiotherapy 10/2017
1	Oral Administration 12/2016